Correlation between phenotypic antibiotic susceptibility and the resistome in Pseudomonas aeruginosa
نویسندگان
چکیده
منابع مشابه
[Antibiotic susceptibility of Pseudomonas aeruginosa].
The susceptibility of 128 clinical isolates of Pseudomonas aeruginosa against amikacin, kanamycin, gentamycin, minocycline, colistin, chloramphenicol, claforan , piperacillin and carbenicillin were tested. Piperacillin, carbenicillin, amikacin and claforan are effective against at least 54% of strains tested. The susceptibilities of microorganisms to antibiotics were evaluated in different poin...
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Pseudomonas aeruginosa is an opportunistic human pathogen. Treatment is complicated by frequent acquired resistance to antipseudomonal therapies. Polyamines (cadaverine, putrescine, spermidine, and spermine) are ubiquitous polycationic compounds essential for all living organisms. In a dose-dependent manner, polyamines increased the susceptibility of P. aeruginosa to 14 beta-lactam antibiotics,...
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Abstract Background and Objective: Cystic fibrosis (CF) is an autosomal recessive genetic disease and Pseudomonas aeruginosa is one of the most common bacteria colonized in CF patients. Growing resistance of this bacterium to antibiotics now a day is a challenge of controlling infection in CF patient. In this study colonization of CF patients with Pseudomonas aeruginosa and antibiotic suscep...
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One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for developing antimicrobial resistance to nearly all available antipseudomonal agents through the selection of chromosomal mutations, leading to the failure of the treatment of severe hospital-acquired or chronic infections. Recent whole-genome sequencing (WGS) data obtained from in vitro assays on the evol...
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CONTEXT Multiple surveillance programmes have reported a decline in antibiotic susceptibility of P. aeruginosa. AIM Our study aimed to study the relationship between the use of antipseudomonal drugs and the development of resistance of P. aerogenosa to these drugs. SETTING AND DESIGN Our study is retrospective. It was conducted in a medical surgical intensive care unit during a five-year pe...
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ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2017
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2017.02.026